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Vol. 28 (2025 year), No. 4, DOI: 10.21443/1560-9278-2025-28-4/2

Simonenkova A. P., Ivanova T. N., Markov V. V.
Optimization of functional food supplements formulations for the prevention of respiratory diseases

Modern preventative medicine and the food industry are focused on developing dietary supplements intended for systematic use in diets for various social and age groups and for the prevention of various diseases. This study has examined individual types of medicinal plant materials and fruit and berry powders used as ingredients in formulating anti-inflammatory and expectorant dietary supplements. To assess the quality of the developed dietary supplements, a comprehensive approach has been used, including a qualimetric assessment of consumer properties and the mathematical method of the generalized Harrington desirability function. Sample 4 of the expectorant dietary supplement has been recognized as optimal in terms of organoleptic properties, with a desirability function value of 0.6977. Sample 5, with a desirability function value of 0.6983, has been determined to be optimal in terms of nutritional value (content of macro- and microelements, vitamins, and phenolic compounds). Based on the organoleptic properties of the anti-inflammatory dietary supplements, formula 4 (desirability function of 0.6971) has been selected as the optimal formulation, with its organoleptic characteristics surpassing those of the control sample. Overall, sample 5, with a desirability function of 0.6908, is considered the optimal supplement based on nutritional value. Due to the targeted pharmacological role of the raw materials used, the inclusion of these components ensures the expectorant and anti-inflammatory effects of the developed dietary supplements.

(in Russian, стр.11, fig. 6, tables. 3, ref 23, AdobePDF, AdobePDF 0 Kb)